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Issue 51, 2020
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Enzyme-mimicking accelerated signal enhancement for visually multiplexed quantitation of telomerase activity

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Abstract

Here, we propose an amplification strategy involving enzyme-mimicking accelerated signal enhancement integrated with a triple-channel volumetric bar-chart chip for visually multiplexed quantitation of telomerase activity. This platform was used for evaluating the telomerase activities from different kinds of cells and a detection limit at the single-cell level was realized without any instrumental assistance.

Graphical abstract: Enzyme-mimicking accelerated signal enhancement for visually multiplexed quantitation of telomerase activity

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Supplementary files

Article information


Submitted
15 Mar 2020
Accepted
05 May 2020
First published
06 May 2020

Chem. Commun., 2020,56, 6969-6972
Article type
Communication

Enzyme-mimicking accelerated signal enhancement for visually multiplexed quantitation of telomerase activity

L. Sun, Q. Zhao, X. Liu, Y. Pan, Y. Gao, J. Yang, Y. Wang and Y. Song, Chem. Commun., 2020, 56, 6969
DOI: 10.1039/D0CC01951H

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