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Issue 53, 2020
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Phthalocyanine–DNA origami complexes with enhanced stability and optical properties

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Abstract

In this communication, electrostatically assembled phthalocyanine (Pc)–DNA origami (DO) complexes are formed and their optical properties are demonstrated. The formation of the complex prevents the Pc aggregation, thus yielding an enhanced optical response and photooxidative resilience towards aggregation in biologically relevant media. Simultaneously, the Pc protects the DO against enzymatic digestion. Both features solve previous drawbacks associated with phthalocyanine photosensitizers and DNA nanocarriers. The studied complexes may find use in technologies related to the photogeneration of singlet oxygen, e.g., photocatalysis, diagnositic arrays and photodynamic therapy.

Graphical abstract: Phthalocyanine–DNA origami complexes with enhanced stability and optical properties

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Supplementary files

Article information


Submitted
13 Mar 2020
Accepted
26 May 2020
First published
27 May 2020

This article is Open Access

Chem. Commun., 2020,56, 7341-7344
Article type
Communication

Phthalocyanine–DNA origami complexes with enhanced stability and optical properties

A. Shaukat, E. Anaya-Plaza, S. Julin, V. Linko, T. Torres, A. de la Escosura and M. A. Kostiainen, Chem. Commun., 2020, 56, 7341
DOI: 10.1039/D0CC01916J

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