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Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu2+ and pH in vitro and in vivo

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Abstract

Novel dual-ratio semiconducting polymer dots (Pdots) with trichromatic-emission in the red, green and blue primary-color regions, are designed as lysosome-targeting nanoprobes for the simultaneous detection and multicolor imaging of pH and Cu2+ in HeLa cells and zebrafish without cross-interference.

Graphical abstract: Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu2+ and pH in vitro and in vivo

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Article information


Submitted
09 Mar 2020
Accepted
22 Jun 2020
First published
22 Jun 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu2+ and pH in vitro and in vivo

Q. Zhang, J. Sun, R. Zhang, X. Chen, N. Chen and F. Gao, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC01811B

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