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Live cell fluorescent stain of bacterial curli and biofilm through supramolecular recognition between bromophenol blue and CsgA

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Abstract

Identification of curli-specific dyes for biofilm communities of microorganisms is an important task. We describe here a curli fluorescent light-up probe called bromophenol blue, which binds to curli via recognizing CsgA. This platform may provide a new perspective for the research on biofilm, amyloid disease and living materials.

Graphical abstract: Live cell fluorescent stain of bacterial curli and biofilm through supramolecular recognition between bromophenol blue and CsgA

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Article information


Submitted
03 Mar 2020
Accepted
25 Mar 2020
First published
25 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Live cell fluorescent stain of bacterial curli and biofilm through supramolecular recognition between bromophenol blue and CsgA

L. Zhang, Z. Li and Z. Chen, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC01643H

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