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Three-dimensional DNA nanostructures for dual-color microRNA imaging in living cells via hybridization chain reaction

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Abstract

A well-defined 3D DNA nanostructure with precise composition was developed by stoichimetric combination of a DNA tetrahedron and Y-shaped DNA, which allowed multiplexed, signal-amplified fluorescence imaging of miRNAs in living cells via hybridization chain reaction.

Graphical abstract: Three-dimensional DNA nanostructures for dual-color microRNA imaging in living cells via hybridization chain reaction

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Article information


Submitted
02 Mar 2020
Accepted
24 Apr 2020
First published
29 Apr 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Three-dimensional DNA nanostructures for dual-color microRNA imaging in living cells via hybridization chain reaction

M. Lv, Z. Wu, R. Yu and J. Jiang, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC01626H

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