Issue 26, 2020
From the journal:

Chemical Communications

Unlocking the direct photocatalytic difluoromethylation of C[double bond, length as m-dash]N bonds†

Alberto F. Garrido-Castro, ORCID logo a   Andrea Gini,a   M. Carmen Maestro ORCID logo *a  and  José Alemán ORCID logo *ab  

* Corresponding authors

a Department of Organic Chemistry, Universidad Autónoma de Madrid, Spain
E-mail: jose.aleman@uam.es, carmen.maestro@uam.es
Web: http://www.uam.es/jose.aleman

b Institute for Advanced Research in Chemical Sciences (IAdChem), Universidad Autónoma de Madrid, Spain

Abstract

The current study presents a direct CF2H radical addition to C[double bond, length as m-dash]N bonds predicated on the photocatalytic activation of commercially available zinc difluoromethanesulfinate. The mild conditions in place lead to impressive structural diversity, as quinoxalinones and dibenzazepines, among others, are successfully functionalized.

Graphical abstract: Unlocking the direct photocatalytic difluoromethylation of C [[double bond, length as m-dash]] N bonds

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Article information

DOI
https://doi.org/10.1039/D0CC01353F
Article type
Communication
Submitted
30 Jan 2020
Accepted
27 Feb 2020
First published
27 Feb 2020
This article is Open Access
Creative Commons BY license

Chem. Commun., 2020,56, 3769-3772

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Unlocking the direct photocatalytic difluoromethylation of C[double bond, length as m-dash]N bonds

A. F. Garrido-Castro, A. Gini, M. C. Maestro and J. Alemán, Chem. Commun., 2020, 56, 3769 DOI: 10.1039/D0CC01353F

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