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Control of microenvironment around enzymes by hydrogels

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Abstract

We prepared enzyme-immobilized hydrogels and investigated the effects of the cross-linking density and polymer properties on their oxidation reaction rate. The oxidation rate of enzyme-immobilized hydrogels increased as the cross-linking density in the hydrogels increased. In addition, we controlled the oxidation rate using hydrogels exhibiting an appropriate interaction with a decoy molecule in the hydrogel.

Graphical abstract: Control of microenvironment around enzymes by hydrogels

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Article information


Submitted
20 Feb 2020
Accepted
05 May 2020
First published
07 May 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Control of microenvironment around enzymes by hydrogels

Y. Kobayashi, K. Kohara, Y. Kiuchi, H. Onoda, O. Shoji and H. Yamaguchi, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC01332C

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