Issue 46, 2020
From the journal:

Chemical Communications

Al centre-powered graphitic nanozyme with high catalytic efficiency for pH-independent chemodynamic therapy of cancer†

Jun Li,‡a   Ke Yi,‡a   Yanli Lei, ORCID logo *a   Zhihe Qing, ORCID logo a   Zhen Zou, ORCID logo a   Yuedong Zhang,a   Haiyan Suna  and  Ronghua Yang ORCID logo *a  

* Corresponding authors

a Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Food Engineering, Changsha University of Science and Technology, Changsha, Hunan 410004, P. R. China
E-mail: Yangrh@pku.edu.cn, leiyanli222@126.com

Abstract

An Al centre-powered graphitic nanozyme derived from a metal organic framework was first developed for a chemodynamic tumor treatment. By virtue of the rapid and efficient generation of ˙OH in the slightly acidic tumor microenvironment, this nanozyme afforded high anti-tumor efficacy both in living cells and in vivo.

Graphical abstract: Al centre-powered graphitic nanozyme with high catalytic efficiency for pH-independent chemodynamic therapy of cancer

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Article information

DOI
https://doi.org/10.1039/D0CC01331E
Article type
Communication
Submitted
20 Feb 2020
Accepted
27 Apr 2020
First published
28 Apr 2020

Chem. Commun., 2020,56, 6285-6288

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Al centre-powered graphitic nanozyme with high catalytic efficiency for pH-independent chemodynamic therapy of cancer

J. Li, K. Yi, Y. Lei, Z. Qing, Z. Zou, Y. Zhang, H. Sun and R. Yang, Chem. Commun., 2020, 56, 6285 DOI: 10.1039/D0CC01331E

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