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Issue 43, 2020
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Boosting two-photon photodynamic therapy with mitochondria-targeting ruthenium–glucose conjugates

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Abstract

Herein, we present a series of dual-targeted ruthenium–glucose conjugates that can function as two-photon absorption (TPA) PDT agents to effectively destroy tumors by preferentially targeting both tumor cells and mitochondria. The in vivo experiments revealed an excellent tumor inhibitory efficiency of the dual-targeted TPA PSs.

Graphical abstract: Boosting two-photon photodynamic therapy with mitochondria-targeting ruthenium–glucose conjugates

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Article information


Submitted
13 Feb 2020
Accepted
20 Apr 2020
First published
20 Apr 2020

Chem. Commun., 2020,56, 5839-5842
Article type
Communication

Boosting two-photon photodynamic therapy with mitochondria-targeting ruthenium–glucose conjugates

J. Liu, X. Liao, K. Xiong, S. Kuang, C. Jin, L. Ji and H. Chao, Chem. Commun., 2020, 56, 5839
DOI: 10.1039/D0CC01148G

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