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Issue 56, 2020
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Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells

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Abstract

We report the synthesis and comprehensive characterization of a new platinum-AIEgen coordination complex. Possessing a high 1O2 quantum yield of 0.75 in water, the complex efficiently kills cisplatin-resistant cancer cells under mild white light irradiation. Its strong fluorescence upon binding with proteins also enables direct visualization of its intracellular distribution.

Graphical abstract: Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells

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Article information


Submitted
01 Feb 2020
Accepted
04 Jun 2020
First published
04 Jun 2020

Chem. Commun., 2020,56, 7785-7788
Article type
Communication

Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells

Z. He, Y. Gao, H. Zhang, X. Wang, F. Meng, L. Luo and B. Z. Tang, Chem. Commun., 2020, 56, 7785
DOI: 10.1039/D0CC00821D

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