A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures

Limin Yang; Xuehan Yin; Panpan Gai; Feng Li

doi:10.1039/D0CC00788A

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A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures†

Limin Yang,^a Xuehan Yin,^a Panpan Gai^a and Feng Li

*^a

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* Corresponding authors

^a College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, People's Republic of China
E-mail: lifeng@qau.edu.cn

Abstract

We developed a label-free homogeneous electrochemical cytosensor for ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures, which avoided expensive labeling and sophisticated immobilization procedures, providing opportunities for precisely detecting cancer cells in clinical applications.

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Article information

DOI: https://doi.org/10.1039/D0CC00788A
Article type: Communication
Submitted: 31 Jan 2020
Accepted: 26 Feb 2020
First published: 26 Feb 2020

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Chem. Commun., 2020,56, 3883-3886

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A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures

L. Yang, X. Yin, P. Gai and F. Li, Chem. Commun., 2020, 56, 3883 DOI: 10.1039/D0CC00788A

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Chemical Communications

A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures†

Abstract

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Article information

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A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures

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