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Reversible redox-responsive 1H/19F MRI molecular probes

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Abstract

Herein we report a pair of redox-responsive manganese complexes Mn(III)/(II)-N,N′-bis(2-hydroxy-4-trifluoromethylbenzyl)ethylenediamine-N,N′-diacetate (HTFBED, L1), which are water soluble and biologically interconvertible, as reversible redox-responsive probes in 1H/19F MRI for detecting and imaging biological redox species, offering a means to access valuable redox information associated with various diseases.

Graphical abstract: Reversible redox-responsive 1H/19F MRI molecular probes

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Article information


Submitted
30 Jan 2020
Accepted
03 Mar 2020
First published
04 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Reversible redox-responsive 1H/19F MRI molecular probes

H. Chen, X. Tang, X. Gong, D. Chen, A. Li, C. Sun, H. Lin and J. Gao, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC00778A

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