Issue 17, 2020
From the journal:

Chemical Communications

Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy†

Jiabao Zhuang,‡a   Hanxiao Yang,‡a   Yue Li,a   Bing Wang,a   Nan Li ORCID logo *a  and  Na Zhao ORCID logo *a  

* Corresponding authors

a Key Laboratory of Macromolecular Science of Shaanxi Province, Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, School of Chemistry & Chemical Engineering, Shaanxi Normal University, 710119 Xi’an, China
E-mail: nli@snnu.edu.cn, nzhao@snnu.edu.cn

Abstract

Two efficient photosensitizers (PSs) with aggregation-induced emission characteristics were designed and synthesized for specific lysosome-targeted photodynamic therapy (PDT). Both PSs efficiently discriminated Gram-positive bacteria from Gram-negative bacteria and killed Gram-positive bacteria through the PDT effect.

Graphical abstract: Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/D0CC00394H
Article type
Communication
Submitted
15 Jan 2020
Accepted
28 Jan 2020
First published
28 Jan 2020

Chem. Commun., 2020,56, 2630-2633

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Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy

J. Zhuang, H. Yang, Y. Li, B. Wang, N. Li and N. Zhao, Chem. Commun., 2020, 56, 2630 DOI: 10.1039/D0CC00394H

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