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Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy

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Abstract

Two efficient photosensitizers (PSs) with aggregation-induced emission characteristics were designed and synthesized for specific lysosome-targeted photodynamic therapy (PDT). Both PSs efficiently discriminated Gram-positive bacteria from Gram-negative bacteria and killed Gram-positive bacteria through the PDT effect.

Graphical abstract: Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy

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Article information


Submitted
15 Jan 2020
Accepted
28 Jan 2020
First published
28 Jan 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy

J. Zhuang, H. Yang, Y. Li, B. Wang, N. Li and N. Zhao, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC00394H

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