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A new FRET probe for ratiometric fluorescence detecting mitochondria-localized drug activation and imaging endogenous hydroxyl radicals in zebrafish

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Abstract

A new FRET probe has been prepared for ratiometric fluorescence detection of hydroxyl radicals. It has been successfully used for detecting mitochondria-localized drug activation in living cells and imaging endogenous hydroxyl radicals in zebrafish gastrointestinal (GI) tracts under normal culturing conditions.

Graphical abstract: A new FRET probe for ratiometric fluorescence detecting mitochondria-localized drug activation and imaging endogenous hydroxyl radicals in zebrafish

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Article information


Submitted
16 Jan 2020
Accepted
09 Mar 2020
First published
10 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

A new FRET probe for ratiometric fluorescence detecting mitochondria-localized drug activation and imaging endogenous hydroxyl radicals in zebrafish

T. Deng, X. Wang, S. Wu, S. Hu, W. Liu, T. Chen, Z. Yu, Q. Xu and F. Liu, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC00382D

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