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A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H2S and its bioimaging applications in living cells and zebrafish

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Abstract

We have synthesized a simple Golgi-targeting H2S fluorescent probe which can detect endogenous and exogenous H2S in cells and zebrafish. In addition, this probe provides a new chemical tool for the detailed study of generation pathways of H2S under Golgi stress response.

Graphical abstract: A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H2S and its bioimaging applications in living cells and zebrafish

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Article information


Submitted
11 Jan 2020
Accepted
03 Mar 2020
First published
04 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H2S and its bioimaging applications in living cells and zebrafish

H. Zhu, C. Liu, C. Liang, B. Tian, H. Zhang, X. Zhang, W. Sheng, Y. Yu, S. Huang and B. Zhu, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC00282H

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