Issue 21, 2020
From the journal:

Chemical Communications

Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA†

Van Thang Nguyen,a   Anup Pandith ORCID logo b  and  Young Jun Seo ORCID logo *ab  

* Corresponding authors

a Department of Bioactive Material Sciences, Jeonbuk National University, South Korea

b Department of Chemistry, Jeonbuk National University, South Korea
E-mail: yseo@jbnu.ac.kr
Fax: +82-63-270-3408
Tel: +82-63-270-3417

Abstract

We have developed a propargylamine-selective dual fluorescence turn-on system, using ylidenemalononitrile enamines, for post-synthetic DNA labeling, allowing the direct monitoring of DNA using dual emission in living cells.

Graphical abstract: Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA

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Article information

DOI
https://doi.org/10.1039/D0CC00255K
Article type
Communication
Submitted
10 Jan 2020
Accepted
03 Feb 2020
First published
04 Feb 2020

Chem. Commun., 2020,56, 3199-3202

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Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA

V. T. Nguyen, A. Pandith and Y. J. Seo, Chem. Commun., 2020, 56, 3199 DOI: 10.1039/D0CC00255K

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