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Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA

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Abstract

We have developed a propargylamine-selective dual fluorescence turn-on system, using ylidenemalononitrile enamines, for post-synthetic DNA labeling, allowing the direct monitoring of DNA using dual emission in living cells.

Graphical abstract: Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA

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Article information


Submitted
10 Jan 2020
Accepted
03 Feb 2020
First published
04 Feb 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA

V. T. Nguyen, A. Pandith and Y. J. Seo, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC00255K

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