Issue 25, 2020
From the journal:

Chemical Communications

Two-photon probes for the endoplasmic reticulum: its detection in a live tissue by two-photon microscopy†

Ji-Woo Choi, ORCID logo ‡a   Seung-Hye Choi,‡a   Seung Taek Hong, ORCID logo a   Mun Seok Kim,b   Seong Shick Ryu,a   Yeo Uk Yoon,b   Kyu Cheol Paik,b   Man So Han,b   Taebo Simac  and  Bong Rae Cho ORCID logo *abd  

* Corresponding authors

a KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea
E-mail: chobr@korea.ac.kr

b Department of Chemistry, Daejin University, 1007 Hoguk-ro, Pocheon-si, Gyeonggi-do 11159, Republic of Korea

c Severance Biomedical Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea

d Department of Chemistry, Korea University, 145 Anam-ro, Sungbuk-gu, Seoul 02841, Republic of Korea

Abstract

We report blue- and green-emitting two-photon probes derived from naphthalene and fluorene derivatives (as fluorophores) and an endoplasmic reticulum (ER) retrieval peptide (KDEL; as an ER-targeting moiety) that can detect the ER in a live cell by both one-photon and two-photon microscopy (TPM) and in a live tissue by TPM.

Graphical abstract: Two-photon probes for the endoplasmic reticulum: its detection in a live tissue by two-photon microscopy

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Article information

DOI
https://doi.org/10.1039/D0CC00236D
Article type
Communication
Submitted
10 Jan 2020
Accepted
24 Feb 2020
First published
25 Feb 2020

Chem. Commun., 2020,56, 3657-3660

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Two-photon probes for the endoplasmic reticulum: its detection in a live tissue by two-photon microscopy

J. Choi, S. Choi, S. T. Hong, M. S. Kim, S. S. Ryu, Y. U. Yoon, K. C. Paik, M. S. Han, T. Sim and B. R. Cho, Chem. Commun., 2020, 56, 3657 DOI: 10.1039/D0CC00236D

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