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Issue 15, 2020
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Recent advances in metal-catalysed asymmetric sequential double hydrofunctionalization of alkynes

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Abstract

In recent years, metal-catalysed asymmetric sequential double hydrofunctionalization of alkynes (ASDHA) has emerged as a powerful strategy to construct valuable chiral products in an atom- and pot-economic manner utilizing readily available feedstocks. In this feature article, recent progress made in this field will be overviewed. Attention will be given to the background, substrate scopes, applications, advances and mechanistic investigations of various asymmetric sequential double hydrofunctionalizations of alkynes.

Graphical abstract: Recent advances in metal-catalysed asymmetric sequential double hydrofunctionalization of alkynes

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Article information


Submitted
04 Jan 2020
Accepted
31 Jan 2020
First published
31 Jan 2020

Chem. Commun., 2020,56, 2229-2239
Article type
Feature Article

Recent advances in metal-catalysed asymmetric sequential double hydrofunctionalization of alkynes

Z. Cheng, J. Guo and Z. Lu, Chem. Commun., 2020, 56, 2229
DOI: 10.1039/D0CC00068J

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