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Issue 26, 2020
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How many cells are enough for single-cell infrared spectroscopy?

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Abstract

The influence of cell number on spectral variability among two different cell types and two states was quantitatively analyzed and evaluated by calculating the similarity distance of the single-cell spectral data obtained from synchrotron infrared microspectroscopy. We found that at least 15 cells are required to achieve robust results with 95% confidence.

Graphical abstract: How many cells are enough for single-cell infrared spectroscopy?

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Supplementary files

Article information


Submitted
04 Jan 2020
Accepted
25 Feb 2020
First published
26 Feb 2020

Chem. Commun., 2020,56, 3773-3776
Article type
Communication

How many cells are enough for single-cell infrared spectroscopy?

Y. Wang, W. Dai, Y. Wang, J. Liu, Z. Liu, Y. Li, X. Li, J. Hu and J. Lü, Chem. Commun., 2020, 56, 3773
DOI: 10.1039/D0CC00067A

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