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Cascade cycling of nicotinamide cofactor in a dual enzyme microsystem

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Abstract

Encapsulation of two enzymes, alcohol dehydrogenase (ADH) and glucose oxidase (GOx), within peroxidase-like tourmaline microparticle (TM)-based colloidosomes was used to construct a functionalized microsystem capable of sustainable cascade cycling of nicotinamide cofactor (NAD+/NADH) via chemical signaling between spatially confined dual-enzyme and active membranes.

Graphical abstract: Cascade cycling of nicotinamide cofactor in a dual enzyme microsystem

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Article information


Submitted
28 Dec 2019
Accepted
28 Jan 2020
First published
28 Jan 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Cascade cycling of nicotinamide cofactor in a dual enzyme microsystem

R. Lv, S. Lin, S. Sun, H. He, F. Zheng, D. Tan, B. Ma and M. He, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC10031H

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