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Host-guest recognition coupled with triple signal amplification endows electrochemiluminescent biosensor with enhanced sensitivity

Abstract

We demonstrate for the first time that the host-guest recognition coupled with triple signal amplification endows the electrochemiluminescent (ECL) biosensor with enhanced sensitivity for uracil DNA glycosylase (UDG) assay. This biosensor exhibits good selectivity and extremely high sensitivity, and it can be used to screen the UDG inhibitors and measure the cellular UDG activity as well.

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Supplementary files

Article information


Submitted
26 Dec 2019
Accepted
11 Feb 2020
First published
11 Feb 2020

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

Host-guest recognition coupled with triple signal amplification endows electrochemiluminescent biosensor with enhanced sensitivity

M. Zhao, L. Cui and C. Zhang, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/C9CC09999A

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