Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 28, 2020
Previous Article Next Article

The elucidation of phospholipid bilayer–small molecule interactions using a combination of phospholipid nanodiscs and solution state NMR techniques

Author affiliations

Abstract

Quantifying phospholipid bilayer–small molecule interactions is vital to the development of new drug candidates and/or medicinal therapies. However, obtaining these data remains problematic. Herein, we detail a phospholipid nanodisc assay which enables the elucidation of these interactions using conventional solution state NMR spectroscopy techniques.

Graphical abstract: The elucidation of phospholipid bilayer–small molecule interactions using a combination of phospholipid nanodiscs and solution state NMR techniques

Back to tab navigation

Supplementary files

Article information


Submitted
23 Dec 2019
Accepted
05 Mar 2020
First published
05 Mar 2020

Chem. Commun., 2020,56, 4015-4018
Article type
Communication

The elucidation of phospholipid bilayer–small molecule interactions using a combination of phospholipid nanodiscs and solution state NMR techniques

G. Townshend, G. S. Thompson, L. J. White, J. R. Hiscock and J. L. Ortega-Roldan, Chem. Commun., 2020, 56, 4015
DOI: 10.1039/C9CC09948D

Social activity

Search articles by author

Spotlight

Advertisements