Jump to main content
Jump to site search


Asymmetric dearomatization of 2-nitrobenzofurans by organocatalyzed one-step Michael addition to access 3,3′-disubstituted oxindoles

Author affiliations

Abstract

An efficient enantioselective dearomatization of 2-nitrobenzofurans was realized via an organocatalyzed one-step Michael addition process. This method provides a facile strategy to access a range of structurally diverse 3,3′-disubstituted oxindoles, which feature an intriguing combination of two privileged motifs including 3-pyrrolyl-substituted-oxindoles and 2,3-dihydrobenzofurans substructures, in excellent results.

Graphical abstract: Asymmetric dearomatization of 2-nitrobenzofurans by organocatalyzed one-step Michael addition to access 3,3′-disubstituted oxindoles

Back to tab navigation

Supplementary files

Article information


Submitted
23 Dec 2019
Accepted
27 Jan 2020
First published
28 Jan 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Asymmetric dearomatization of 2-nitrobenzofurans by organocatalyzed one-step Michael addition to access 3,3′-disubstituted oxindoles

Z. Ge, L. Yang, Y. You, Z. Wang, K. Xie, M. Zhou, J. Zhao and W. Yuan, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09939E

Social activity

Search articles by author

Spotlight

Advertisements