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Oxyanion transport across lipid bilayers: direct measurements in large and giant unilamellar vesicles

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Abstract

A simple di(thioamido)carbazole 1 serves as a potent multispecific transporter for various biologically relevant oxyanions, such as drugs, metabolites and model organic phosphate. The transport kinetics of a wide range of oxyanions can be easily quantified by a modified lucigenin assay in both large and giant unilamellar vesicles.

Graphical abstract: Oxyanion transport across lipid bilayers: direct measurements in large and giant unilamellar vesicles

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Article information


Submitted
10 Jan 2020
Accepted
24 Mar 2020
First published
25 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Oxyanion transport across lipid bilayers: direct measurements in large and giant unilamellar vesicles

K. M. Bąk, B. van Kolck, K. Maslowska-Jarzyna, P. Papadopoulou, A. Kros and M. J. Chmielewski, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09888G

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