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Modulation of cyclic topology toward enhanced drug delivery, from linear and tadpole-like to dumbbell-shaped copolymers

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Abstract

In this study, an efficient strategy for the synthesis of dumbbell-shaped amphiphilic copolymers with cyclic moieties as the two bells was developed and the enhanced performance of dumbbell-shaped copolymers for controlled drug release because of the simultaneous introduction of two macrocycles was disclosed.

Graphical abstract: Modulation of cyclic topology toward enhanced drug delivery, from linear and tadpole-like to dumbbell-shaped copolymers

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Article information


Submitted
20 Dec 2019
Accepted
03 Feb 2020
First published
04 Feb 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Modulation of cyclic topology toward enhanced drug delivery, from linear and tadpole-like to dumbbell-shaped copolymers

G. Kang, Y. Liu, L. Li, L. Sun, W. Ma, C. Meng, L. Ma, G. Zheng, C. Chang and H. Wei, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09878J

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