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pH stimulus-disaggregated BODIPY: an activated photodynamic/photothermal sensitizer applicable to tumor ablation

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Abstract

Herein, we report a pH stimulus-disaggregated BODIPY sensitizer (PTS) with low background-toxicity for achieving activated photodynamic/photothermal tumor therapy. Both the photodynamic and photothermal properties of PTS can be activated under acidic conditions, and PTS exhibits excellent antitumor properties, which is revealed by both in vitro and in vivo tests.

Graphical abstract: pH stimulus-disaggregated BODIPY: an activated photodynamic/photothermal sensitizer applicable to tumor ablation

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Article information


Submitted
17 Dec 2019
Accepted
08 Jan 2020
First published
08 Jan 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

pH stimulus-disaggregated BODIPY: an activated photodynamic/photothermal sensitizer applicable to tumor ablation

Y. Liu, C. Xu, L. Teng, H. Liu, T. Ren, S. Xu, X. Lou, H. Guo, L. Yuan and X. Zhang, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09790B

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