Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 27, 2020
Previous Article Next Article

Peroxidation of 3,4-dihydro-1,4-benzoxazin-2-ones

Author affiliations

Abstract

The sp3-C–H peroxidation of 3,4-dihydro-1,4-benzoxazin-2-ones was achieved under mild and simple catalyst-free reaction conditions. A range of biologically important alkylated benzoxazinone peroxides are synthesized in high yield with a good functional group tolerance. The C(sp3)-OO bond was constructed efficiently and could be further converted into C(sp3)–C(sp3), C(sp3)–C(sp2), C(sp3)–C(sp), C–P and C[double bond, length as m-dash]O bonds by late-stage functional group transformations.

Graphical abstract: Peroxidation of 3,4-dihydro-1,4-benzoxazin-2-ones

Back to tab navigation

Supplementary files

Article information


Submitted
17 Dec 2019
Accepted
26 Feb 2020
First published
26 Feb 2020

Chem. Commun., 2020,56, 3895-3898
Article type
Communication

Peroxidation of 3,4-dihydro-1,4-benzoxazin-2-ones

J. Wang, X. Bao, J. Wang and C. Huo, Chem. Commun., 2020, 56, 3895
DOI: 10.1039/C9CC09778C

Social activity

Search articles by author

Spotlight

Advertisements