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Small-sized copolymeric nanoparticles for tumor penetration and intracellular drug release

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Abstract

Poor solid-tumor penetration of nanocarriers limits the drug efficacy. Herein, small-sized copolymeric nanoparticles are prepared for delivering the chemotherapeutic drug DOX into solid tumors deeply and releasing the drug effectively. These small-sized copolymeric nanoparticles represent substantial potential for clinical translation.

Graphical abstract: Small-sized copolymeric nanoparticles for tumor penetration and intracellular drug release

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Article information


Submitted
14 Dec 2019
Accepted
10 Jan 2020
First published
10 Jan 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Small-sized copolymeric nanoparticles for tumor penetration and intracellular drug release

C. Zhu, L. Zang, D. Zheng, H. Cao and X. Liu, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09716C

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