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Issue 14, 2020
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Copper-mediated tandem ring-opening/cyclization reactions of cyclopropanols with aryldiazonium salts: synthesis of N-arylpyrazoles

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Abstract

A general method for the synthesis of structurally diverse N-arylpyrazoles from readily available cyclopropanols and aryldiazonium salts is disclosed. The reaction was conducted at room temperature within minutes with a broad substrate scope and excellent regioselectivity.

Graphical abstract: Copper-mediated tandem ring-opening/cyclization reactions of cyclopropanols with aryldiazonium salts: synthesis of N-arylpyrazoles

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Article information


Submitted
12 Dec 2019
Accepted
17 Jan 2020
First published
17 Jan 2020

Chem. Commun., 2020,56, 2202-2205
Article type
Communication

Copper-mediated tandem ring-opening/cyclization reactions of cyclopropanols with aryldiazonium salts: synthesis of N-arylpyrazoles

J. Liu, E. Xu, J. Jiang, Z. Huang, L. Zheng and Z. Liu, Chem. Commun., 2020, 56, 2202
DOI: 10.1039/C9CC09657D

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