Jump to main content
Jump to site search

Issue 7, 2020
Previous Article Next Article

Palladium(ii)-catalyzed vinylic geminal double C–H activation and alkyne annulation reaction: synthesis of pentafulvenes

Author affiliations

Abstract

The first transition-metal-catalyzed vinylic geminal double C(sp2)–H activation and di-substituted alkyne annulation reaction is reported. This palladium(II)-catalyzed, amide directed reaction of vinylic compounds with di-substituted alkynes offers an efficient synthetic path to pentafulvenes, which are very important compounds because of their bioactivity and interesting optical properties. A FeCl3-mediated transformation of pentafulvenes to fluorescent cyclopenta[b]quinolines is also developed.

Graphical abstract: Palladium(ii)-catalyzed vinylic geminal double C–H activation and alkyne annulation reaction: synthesis of pentafulvenes

Back to tab navigation

Supplementary files

Article information


Submitted
10 Dec 2019
Accepted
13 Dec 2019
First published
17 Dec 2019

Chem. Commun., 2020,56, 1133-1136
Article type
Communication

Palladium(II)-catalyzed vinylic geminal double C–H activation and alkyne annulation reaction: synthesis of pentafulvenes

J. Phukon and S. Gogoi, Chem. Commun., 2020, 56, 1133
DOI: 10.1039/C9CC09564K

Social activity

Search articles by author

Spotlight

Advertisements