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Taxodisones A and B: bioactive C30-terpenes with new skeletons from Taxodium distichum and their biosynthetic origin

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Abstract

Taxodisones A and B, C30-terpenes with an unprecedented tetracyclo[12.4.0.0.2,709,14]octodecane core, were isolated from the seeds of Taxodium distichum. Their structures, including their configurations, were unambiguously determined. Their biomimetic synthesis suggests that they stem from diterpenes and monoterpenes, and not from squalene or oxidosqualene. In addition, their bioactivities were also evaluated.

Graphical abstract: Taxodisones A and B: bioactive C30-terpenes with new skeletons from Taxodium distichum and their biosynthetic origin

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Article information


Submitted
04 Dec 2019
Accepted
06 Feb 2020
First published
06 Feb 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Taxodisones A and B: bioactive C30-terpenes with new skeletons from Taxodium distichum and their biosynthetic origin

W. Wang, X. Liu, M. Zhang, B. Lin, D. Zhu, L. Li, C. Chen, C. Han, J. Luo and L. Kong, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09433D

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