Taxodisones A and B: bioactive C30-terpenes with new skeletons from Taxodium distichum and their deep origin
Taxodisones A and B, C30¬-terpenes with an unprecedented tetracyclo[22.214.171.124.2,709,14]octodecane core, were isolated from the seeds of Taxodium distichum. Their structures including configurations were unambiguously determined. Their biomimetic synthesis was described to suggest they stemmed from diterpenes and monoterpenes not from squalene or oxidosqualene. In addition, their bioactivities were also evaluated.