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Taxodisones A and B: bioactive C30-terpenes with new skeletons from Taxodium distichum and their deep origin

Abstract

Taxodisones A and B, C30¬-terpenes with an unprecedented tetracyclo[12.4.0.0.2,709,14]octodecane core, were isolated from the seeds of Taxodium distichum. Their structures including configurations were unambiguously determined. Their biomimetic synthesis was described to suggest they stemmed from diterpenes and monoterpenes not from squalene or oxidosqualene. In addition, their bioactivities were also evaluated.

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Article information


Submitted
04 Dec 2019
Accepted
06 Feb 2020
First published
06 Feb 2020

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

Taxodisones A and B: bioactive C30-terpenes with new skeletons from Taxodium distichum and their deep origin

W. Wang, X. Liu, M. Zhang, B. Lin, D. Zhu, L. Li, C. Chen, C. Han, J. Luo and L. Kong, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/C9CC09433D

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