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Palladium-catalyzed cascade reactions of enynones and isocyanides: access towards functionalized ketenimine and its application

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Abstract

Palladium-catalyzed cascade reactions of enynones and isocyanides have been disclosed. This strategy allows for the synthesis of structurally unusual furan-incorporated ketenimines, which are stable and can undergo a formal [4+1] annulation with another isocyanide to yield indenone derivatives.

Graphical abstract: Palladium-catalyzed cascade reactions of enynones and isocyanides: access towards functionalized ketenimine and its application

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Article information


Submitted
02 Dec 2019
Accepted
13 Mar 2020
First published
13 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Palladium-catalyzed cascade reactions of enynones and isocyanides: access towards functionalized ketenimine and its application

J. Huang, F. Li, L. Cui, S. Su, X. Jia and J. Li, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09363J

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