Jump to main content
Jump to site search


Controlling the kinetics of interaction between microtubules and kinesins over a wide temperature range using the deep-sea osmolyte trimethylamine N-oxide

Author affiliations

Abstract

Trimethylamine N-oxide is found to be effective in regulating the interaction between microtubules and kinesins over a wide temperature range. The lifetime of the motility of microtubules on kinesins at high temperatures is prolonged using trimethylamine N-oxide. The activation energy of microtubule motility is increased by trimethylamine N-oxide. Prolonged operation at high temperatures decreased the activation energy of MT motility despite the increase in concentration of trimethylamine N-oxide.

Graphical abstract: Controlling the kinetics of interaction between microtubules and kinesins over a wide temperature range using the deep-sea osmolyte trimethylamine N-oxide

Back to tab navigation

Supplementary files

Article information


Submitted
30 Nov 2019
Accepted
23 Dec 2019
First published
26 Dec 2019

Chem. Commun., 2020, Advance Article
Article type
Communication

Controlling the kinetics of interaction between microtubules and kinesins over a wide temperature range using the deep-sea osmolyte trimethylamine N-oxide

T. Munmun, A. Md. R. Kabir, Y. Katsumoto, K. Sada and A. Kakugo, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09324A

Social activity

Search articles by author

Spotlight

Advertisements