Jump to main content
Jump to site search


Low-toxicity carbon quantum dots derived from gentamicin sulfate to combat antibiotic resistance and eradicate mature biofilms

Author affiliations

Abstract

Carbon quantum dots derived from gentamicin sulfate are directly developed by facile calcination at different temperatures. A promising nanomaterial, CQD180, even shows a much superior antibacterial activity compared with the antibiotic counterpart and low drug resistance, by preserving the active structure of the starting materials and providing an additional antibacterial mode arising from the positive charge surface and induced reactive oxygen species simultaneously. Moreover, CQD180 can effectively disrupt mature Staphylococcus aureus biofilm and selectively eliminate bacteria over mammalian cells.

Graphical abstract: Low-toxicity carbon quantum dots derived from gentamicin sulfate to combat antibiotic resistance and eradicate mature biofilms

Back to tab navigation

Supplementary files

Article information


Submitted
27 Nov 2019
Accepted
14 Jan 2020
First published
28 Jan 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Low-toxicity carbon quantum dots derived from gentamicin sulfate to combat antibiotic resistance and eradicate mature biofilms

P. Li, S. Liu, W. Cao, G. Zhang, X. Yang, X. Gong and X. Xing, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09223D

Social activity

Search articles by author

Spotlight

Advertisements