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Target-modulated sensitization of upconversion luminescence by NIR-emissive quantum dots: a new strategy to construct upconversion biosensors

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Abstract

We herein used Ag2Se quantum dots (QDs) as a target-modulated sensitizer for upconversion nanoparticles (UCNPs) and the target thrombin as the sensitizing switch to construct a biosensor, circumventing the limited luminescence resonance energy transfer (LRET) efficiency of UCNPs, with enhanced signal-to-background ratio (SBR) and assay sensitivity.

Graphical abstract: Target-modulated sensitization of upconversion luminescence by NIR-emissive quantum dots: a new strategy to construct upconversion biosensors

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Article information


Submitted
27 Nov 2019
Accepted
13 Jan 2020
First published
13 Jan 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

Target-modulated sensitization of upconversion luminescence by NIR-emissive quantum dots: a new strategy to construct upconversion biosensors

T. Yu, D. Wei, Z. Li, L. Pan, Z. Zhang, Z. Tian and Z. Liu, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC09220J

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