Jump to main content
Jump to site search

Issue 11, 2020
Previous Article Next Article

Dicarbonylative benzannulation of 3-acetoxy-1,4-enynes with CO and silylboranes by Pd and Cu cooperative catalysis: one-step access to 3-hydroxyarylacylsilanes

Author affiliations

Abstract

A new, general Pd/Cu-cocatalysed dicarbonylative benzannulation of 3-acetoxy-1,4-enynes with CO and silylboranes is described. The method utilizes CO as both a one-carbon (C1) unit and an external addition functional reagent to achieve an unprecedented dicarbonylative benzannulation process, and represents a facile, efficient route to 3-hydroxyarylacylsilanes. Mechanistically, the silyl-Cu intermediate formed from CuF2 and silylboranes, and silyl-Pd intermediate generated by transmetallation are two key factors for successfully targeting the reaction and selectivity.

Graphical abstract: Dicarbonylative benzannulation of 3-acetoxy-1,4-enynes with CO and silylboranes by Pd and Cu cooperative catalysis: one-step access to 3-hydroxyarylacylsilanes

Back to tab navigation

Supplementary files

Article information


Submitted
21 Nov 2019
Accepted
08 Jan 2020
First published
08 Jan 2020

Chem. Commun., 2020,56, 1669-1672
Article type
Communication

Dicarbonylative benzannulation of 3-acetoxy-1,4-enynes with CO and silylboranes by Pd and Cu cooperative catalysis: one-step access to 3-hydroxyarylacylsilanes

L. Wu, L. Yang, J. Li and Q. Wang, Chem. Commun., 2020, 56, 1669
DOI: 10.1039/C9CC09077K

Social activity

Search articles by author

Spotlight

Advertisements