Jump to main content
Jump to site search


Ratiometric Detection of Amyloid-beta Aggregation by a Dual-Emissive Tris-heteroleptic Ruthenium Complex

Abstract

A dual-emissive tris-heteroleptic ruthenium complex is designed, synthesized and applied for the ratiometric photoluminescent detection of Amyloid-beta (A-beta) aggregation in both steady and transient states. The A-beta aggregation is supported by transmission electron microscopy and confocal laser scanning microscopy analysis. In addition, molecular docking calculations have been performed to gain insights into the interaction mode between the ruthenium complex and A-beta fibrils.

Back to tab navigation

Supplementary files

Article information


Submitted
14 Nov 2019
Accepted
14 Jan 2020
First published
14 Jan 2020

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

Ratiometric Detection of Amyloid-beta Aggregation by a Dual-Emissive Tris-heteroleptic Ruthenium Complex

J. Shao, S. Wu, J. Ma, Z. Gong, T. Sun, Y. Jin, R. Yang, B. Sun and Y. Zhong, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/C9CC08909H

Social activity

Search articles by author

Spotlight

Advertisements