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HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation

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Abstract

Reported herein is the development of a user-friendly platform for simple and transformative automation based on standard HPLC equipment. We showcase how the improved platform works in application to the completely automated, a “press of the button,” synthesis of various glycan sequences.

Graphical abstract: HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation

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Article information


Submitted
13 Nov 2019
Accepted
03 Jan 2020
First published
03 Jan 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation

M. Panza, K. J. Stine and A. V. Demchenko, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC08876H

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