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Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

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Abstract

Herein, a novel two-photon ratiometric fluorescence assay was proposed for monitoring endogenous steroid sulfatase (STS) activity, which could be applied for the ratiometric imaging of STS activity in the endoplasmic reticulum of living cells and tissues and also could be used to distinguish estrogen-dependent tumor cells from other types of cells.

Graphical abstract: Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

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Article information


Submitted
06 Nov 2019
Accepted
19 Dec 2019
First published
19 Dec 2019

Chem. Commun., 2020, Advance Article
Article type
Communication

Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

W. Li, S. Yin, X. Gong, W. Xu, R. Yang, Y. Wan, L. Yuan and X. Zhang, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC08672B

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