Jump to main content
Jump to site search


Ruthenium-catalyzed meta-C–H bond alkylation of aryl 2-pyridyl ketones

Author affiliations

Abstract

The first example of meta-selective CAr–H bond functionalization of aryl 2-pyridyl ketones has been developed using [Ru(p-cymene)Cl2]2 as the catalyst and alkyl bromide as the coupling reagent. This development provides an efficient strategy for modifying the meta-position of aryl 2-pyridyl ketone skeletons, which are found in various functional molecules.

Graphical abstract: Ruthenium-catalyzed meta-C–H bond alkylation of aryl 2-pyridyl ketones

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Nov 2019, accepted on 28 Nov 2019 and first published on 29 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC08624B
Chem. Commun., 2020, Advance Article

  •   Request permissions

    Ruthenium-catalyzed meta-C–H bond alkylation of aryl 2-pyridyl ketones

    G. Li, C. Jia, X. Cai, L. Zhong, L. Zou and X. Cui, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC08624B

Search articles by author

Spotlight

Advertisements