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Issue 7, 2020
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The optimization of cancer photodynamic therapy by utilization of a pi-extended porphyrin-type photosensitizer in combination with MITO-Porter

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Abstract

The uncontrolled production of reactive oxygen species during photodynamic therapy (PDT) induces oxidative stress. The full potential of PDT is accomplished by delivery of a pi-extended porphyrin-type photosensitizer into mitochondria of tumor cells using a MITO-Porter, a mitochondrial targeting nanodevice. This strategy can be implemented for innovative cancer therapy.

Graphical abstract: The optimization of cancer photodynamic therapy by utilization of a pi-extended porphyrin-type photosensitizer in combination with MITO-Porter

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Article information


Submitted
02 Nov 2019
Accepted
13 Dec 2019
First published
16 Dec 2019

Chem. Commun., 2020,56, 1145-1148
Article type
Communication

The optimization of cancer photodynamic therapy by utilization of a pi-extended porphyrin-type photosensitizer in combination with MITO-Porter

Satrialdi, R. Munechika, V. Biju, Y. Takano, H. Harashima and Y. Yamada, Chem. Commun., 2020, 56, 1145
DOI: 10.1039/C9CC08563G

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