Issue 17, 2020
From the journal:

Chemical Communications

Building an anti-interfering DNAzyme-powered micromachine resistant to being inhibited by biological matrices†

Peng Yang,a   Ping Deng,b   Huan Du,a   Xin Hou,c   Jie Zhang,d   Junbo Chen, ORCID logo *a   Xiandeng Hou ORCID logo ac  and  Rongxing Zhou ORCID logo *d  

* Corresponding authors

a Analytical & Testing Center, Sichuan University, 29 Wangjiang Road, Chengdu, Sichuan 610064, China
E-mail: junbochen@scu.edu.cn

b Nephrology Division, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, China

c Key Lab of Green Chem & Tech of MOE, and College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, Sichuan 610064, China

d Biliary Surgical Department of West China Hospital, Sichuan University, Chengdu, Sichuan 610064, China
E-mail: zhourongxing@163.com

Abstract

A DNAzyme-powered micromachine with anti-interfering properties and displaying resistance to being inhibited by biological matrices was built. This micromachine was able to respond to a specific target in high-concentration serum or whole blood.

Graphical abstract: Building an anti-interfering DNAzyme-powered micromachine resistant to being inhibited by biological matrices

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Article information

DOI
https://doi.org/10.1039/C9CC08515G
Article type
Communication
Submitted
31 Oct 2019
Accepted
13 Jan 2020
First published
15 Jan 2020

Chem. Commun., 2020,56, 2658-2661

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Building an anti-interfering DNAzyme-powered micromachine resistant to being inhibited by biological matrices

P. Yang, P. Deng, H. Du, X. Hou, J. Zhang, J. Chen, X. Hou and R. Zhou, Chem. Commun., 2020, 56, 2658 DOI: 10.1039/C9CC08515G

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