Ir(iii)-Catalyzed direct C–H functionalization of N-phenylacetamide with α-diazo quinones: a novel strategy for producing 2-hydroxy-2′-amino-1,2′-biaryl scaffolds

Abstract

α-Diazo quinones were applied in an Ir(III)-catalyzed direct C–H functionalization assisted by N-phenylacetamide for the construction of highly functionalized 2-hydroxy-2′-amino-1,1′-biaryl scaffolds in good to excellent yields. This strategy features operational simplicity, atom- and step-economy and high efficiency.