Issue 1, 2020
From the journal:

Chemical Communications

Versatile symport transporters based on cyclic peptide dimers†

Alberto Fuertes, ORCID logo a   Manuel Amorín ORCID logo *a  and  Juan R. Granja ORCID logo *a  

* Corresponding authors

a Singular Research Centre in Chemical Biology and Molecular Materials, (CIQUS), Organic Chemistry Department, University of Santiago de Compostela (USC), Santiago de Compostela, Spain
E-mail: manuel.amorin@usc.es, juanr.granja@usc.es

Abstract

We present the synthesis and transmembrane transport properties of a new family of tris-pyridine-decorated cyclic peptides. These molecules are designed to self-assemble into dimeric shuttles in nonpolar media, which act as symport ionophores in which, apparently, the tris-pyridine scaffold complexes both cations and anions with high potency and efficacy.

Graphical abstract: Versatile symport transporters based on cyclic peptide dimers

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Article information

DOI
https://doi.org/10.1039/C9CC06644F
Article type
Communication
Submitted
26 Aug 2019
Accepted
12 Nov 2019
First published
15 Nov 2019

Chem. Commun., 2020,56, 46-49

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Versatile symport transporters based on cyclic peptide dimers

A. Fuertes, M. Amorín and J. R. Granja, Chem. Commun., 2020, 56, 46 DOI: 10.1039/C9CC06644F

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