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Liposome modified with bio-substance for cancer treatment

Abstract

In recent years, liposomes have been used in the field of biomedicine and have achieved many significant results. Because of the unique characteristics of liposomes, they can be loaded with many other nanocarriers, such as biologically active substances. Liposomes is made of lipid bilayers, which are very similar with cell membranes. They have many biological and technical advantages, and have even been used in clinical practice since their unique structure. As liposomes have hydrophobic cavities and hydrophilic cavities, they can simultaneously load hydrophobic and hydrophilic drugs. This causes the increasement of drug loading efficiency and therapeutic capacity. Different therapeutic effects are achieved by different methods, such as place the biological materials in the middle of the bilayer structure of liposome or encapsulating the them in the liposome. By these methods, bio-simulated liposomes can achieve considerable cancer treatment effects. Now liposomes have become an independent platform and play an important role in many aspects. In this review, we emphasis the use of liposomes composed with biomaterials for the treatment of cancer. These include the liposomes that mimic mammalian cells, bacteria, and viruses.

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Article information


Submitted
10 Sep 2020
Accepted
12 Oct 2020
First published
13 Oct 2020

Biomater. Sci., 2020, Accepted Manuscript
Article type
Review Article

Liposome modified with bio-substance for cancer treatment

Y. Li, H. Cong, S. Wang, Y. Shen and B. Yu, Biomater. Sci., 2020, Accepted Manuscript , DOI: 10.1039/D0BM01531H

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