Jump to main content
Jump to site search


A lateral flow biosensor based on gold nanoparticles detects four hemorrhagic fever viruses

Abstract

: The pathogen of a viral hemorrhagic fever (VHF), which is harmful to human health, is a hemorrhagic fever virus. Clinicians have long needed convenient and sensitive point-of-care rapid diagnostic tests (RDTs) for hemorrhagic fever virus. Commonly used methods for pathogen detection rely on conventional culture-based tests, antibody-based assays and polymerase chain reaction (PCR)-based techniques. However, these methods are costly, laborious and time-consuming. Herein, we present a simple and sensitive biosensor for the rapid detection of hemorrhagic fever virus. For this assay, we develop lateral flow biosensors (LFBs) based on magnetic beards and nicking enzyme-assisted isothermal strand-displacement amplification (SDA) for the detection of hemorrhagic fever virus. The detection limit of this assay is 10 fM.

Back to tab navigation

Article information


Submitted
07 Jun 2020
Accepted
05 Oct 2020
First published
07 Oct 2020

Anal. Methods, 2020, Accepted Manuscript
Article type
Paper

A lateral flow biosensor based on gold nanoparticles detects four hemorrhagic fever viruses

J. Zhao, S. Fang, L. Zeng, Z. He and Y. Liu, Anal. Methods, 2020, Accepted Manuscript , DOI: 10.1039/D0AY01137A

Social activity

Search articles by author

Spotlight

Advertisements