Issue 23, 2020

A cytosolically localized far-red to near-infrared rhodamine-based fluorescent probe for calcium ions

Abstract

Ca2+ is one of the most important second messengers in cells. A far-red to near-infrared (NIR) Ca2+ fluorescent probe is useful for multi-color imaging in GFP or YFP-expressing biosamples. Here we developed a cytosolically localized far-red to NIR rhodamine-based fluorescent probe for Ca2+, CaSiR-2 AM, while rhodamine dyes are basically localized to mitochondria or lysosomes in cells.

Graphical abstract: A cytosolically localized far-red to near-infrared rhodamine-based fluorescent probe for calcium ions

Supplementary files

Article information

Article type
Paper
Submitted
31 Aug 2020
Accepted
22 Sep 2020
First published
23 Sep 2020

Analyst, 2020,145, 7736-7740

Author version available

A cytosolically localized far-red to near-infrared rhodamine-based fluorescent probe for calcium ions

K. Numasawa, K. Hanaoka, T. Ikeno, H. Echizen, T. Ishikawa, M. Morimoto, T. Komatsu, T. Ueno, Y. Ikegaya, T. Nagano and Y. Urano, Analyst, 2020, 145, 7736 DOI: 10.1039/D0AN01739F

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