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Phenyl doped graphitic carbon nitride nanosheets for sensing of copper ions in living cells

Abstract

Copper (Cu) is a vital mental element for human and animals. Monitoring and evaluating the concentration level of Cu2+ in biological body is an effective way to prevent a variety of diseases. In this work, phenyl doped graphitic carbon nitride (PDCN) nanosheets with strong green fluorescence exhibited a sensitive and selective detection for Cu2+ with linear range from 0.1-2 μmol L-1. Furthermore, fluorescent imaging was applied to semiquantitatively detect Cu2+ in HeLa cells using PDCN nanosheets as the probe, which can avoid the interference of background autofluorescence. This work provided a low-cost and biological friendly fluorescent probe to monitor the concentration level of Cu2+ in living cell.

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Supplementary files

Article information


Submitted
20 Apr 2020
Accepted
08 May 2020
First published
08 May 2020

Analyst, 2020, Accepted Manuscript
Article type
Paper

Phenyl doped graphitic carbon nitride nanosheets for sensing of copper ions in living cells

Z. Song, Y. Xu and L. Guo, Analyst, 2020, Accepted Manuscript , DOI: 10.1039/D0AN00795A

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