Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Nanoparticle and microorganism detection with a side-micron-orifice-based resistive pulse sensor

Author affiliations

Abstract

This paper presents the detection of nanoparticles and microorganisms using a recently developed side-orifice-based resistive pulse sensor (SO-RPS). By decreasing the channel height of the detection section of the SO-RPS, the detection sensitivity was increased and an average signal to noise ratio (S/N) of about 3 was achieved for 100 nm polystyrene particles. It was also found that spherical particles generate symmetrical signals. Algae with irregular shapes generate signals with more complex patterns. A scatter plot of signal magnitude versus signal width was proven to be reliable for differentiating bacteria from the nanoparticles and two types of algae. The side orifice for detecting heterogeneous nanoparticles and microorganisms is advantageous to avoid orifice clogging and the large flow resistance.

Graphical abstract: Nanoparticle and microorganism detection with a side-micron-orifice-based resistive pulse sensor

Back to tab navigation

Article information


Submitted
06 Apr 2020
Accepted
07 Jun 2020
First published
08 Jun 2020

Analyst, 2020, Advance Article
Article type
Paper

Nanoparticle and microorganism detection with a side-micron-orifice-based resistive pulse sensor

Y. Song, T. Zhou, Q. Liu, Z. Liu and D. Li, Analyst, 2020, Advance Article , DOI: 10.1039/D0AN00679C

Social activity

Search articles by author

Spotlight

Advertisements